Chlorosulfonyl isocyanate → HCID 18973100, compound

HRID 2394354Notes

Reaction equation

HRID 2394354 reaction equation
[C:1]([CH:9]1[C:17]2[C:12](=[CH:13][C:14]([Cl:18])=[CH:15][N:16]=2)[NH:11][C:10]1=[O:19])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:20](=[O:26])=[N:21]S(Cl)(=O)=O>C(#N)C>[C:1]([CH:9]1[C:17]2[C:12](=[CH:13][C:14]([Cl:18])=[CH:15][N:16]=2)[N:11]([C:20]([NH2:21])=[O:26])[C:10]1=[O:19])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 70918Chlorosulfonyl isocyanateHCID 18973084HCID 18973084, compound2×

Product 1

HCID 18973100HCID 18973100, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The title compound was prepared from 3-benzoyl-6-chloro-4-azaoxindole (Example 14) according to the procedure of Example 2C, using 3-benzoyl-6-chloro-4-azaoxindole (500 mg, 1.83 mmol), N-chlorosulfonyl isocyanate (0.24 mL), 2.76 mmol) and acetonitrile (20 mL). The crude product was recrystallized from acetonitrile/chloroform. Yield: 121 mg (21%).

Workup

  1. customThe crude product was recrystallized from acetonitrile/chloroform

Sources & evidence

ORD record
ord-d3925f720ceb4dce888b4ec8fe839b62
Source dataset
uspto-grants-1998_09
Patent number
US05811432

Reaction notes

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