Chlorosulfonyl isocyanate → HCID 18973040, compound

HRID 2394355Notes

Reaction equation

HRID 2394355 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]([C:12](=[O:19])[C:13]3[S:17][CH:16]=[C:15]([Cl:18])[CH:14]=3)[C:7](=[O:11])[NH:8]2)=[N:4][CH:3]=1.[C:20](=[O:26])=[N:21]S(Cl)(=O)=O>C(#N)C>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]([C:12](=[O:19])[C:13]3[S:17][CH:16]=[C:15]([Cl:18])[CH:14]=3)[C:7](=[O:11])[N:8]2[C:20]([NH2:21])=[O:26])=[N:4][CH:3]=1

Participants

4

Reactant 2

HCID 70918Chlorosulfonyl isocyanateHCID 18973069HCID 18973069, compound2×

Product 1

HCID 18973040HCID 18973040, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The title compound was prepared from 6-chloro-3-(4-chloro-2-thenoyl)-4-azaoxindole according to the procedure of Example 2C using 6-chloro-3-(4-chloro-2-thenoyl)-4-azaoxindole (850 mg, 2.7 mmol), N-chlorosulfonyl isocyanate (0.35 mL, 4.0 mmol) and acetonitrile (30 mL). The crude product was recrystallized from acetic acid. Yield: 280 mg (29%).

Workup

  1. customThe crude product was recrystallized from acetic acid

Sources & evidence

ORD record
ord-5bee6e759c054eb9ab899befd6ffe6f4
Source dataset
uspto-grants-1998_09
Patent number
US05811432

Reaction notes

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