Benzoyl chloride → HCID 18973532, compound

HRID 2394394Notes

Reaction equation

HRID 2394394 reaction equation
[NH:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH:10]=[O:11])[C:4]=2[CH:3]=[CH:2]1.[C:12](Cl)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:12]([N:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH:10]=[O:11])[C:4]=2[CH:3]=[CH:2]1)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 333703Indole-4-carboxaldehyde

Product 1

HCID 18973532HCID 18973532, compoundYield 20.9%

Procedure

The same procedures used in Example 11 were repeated except for using 725 mg of indole-4-carbaldehyde and 773 mg of benzoyl chloride instead of phenylacetyl chloride to give 260 mg of 1-benzoylindole-4-carbaldehyde as colorless crystals. The yield thereof was found to be 21%.

Sources & evidence

ORD record
ord-100b6ec5154540d4bab8faff406ea7eb
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

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