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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2394407Generated: November 1, 2026

Indole-4-carboxaldehyde → HCID 18973318, compound

https://huagongshe.com/reaction/2394407

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-4-carboxaldehydeHCID 333703—
Reactant4-(Bromomethyl)-1,2-difluorobenzeneHCID 581436—
ProductHCID 18973318HCID 1897331897.4%

Reaction Steps

The same procedures used in Example 1 were repeated except for using 725 mg of indole-4-carbaldehyde and 1.14 g of 3,4-difluorobenzyl bromide in place of the benzyl bromide used in Example 1 to give 1.32 g of 1-(3,4-difluorobenzyl)indole-4-carbaldehyde as a yellow oily substance. The yield thereof was found to be 97%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05811439
Source datasetuspto-grants-1998_09
ORD IDord-c6261c21f4754b4e84ee92f6abb1c473
Source noteuspto-grants-1998_09