Indole-4-carboxaldehyde → HCID 18973407, compound

HRID 2394410Notes

Reaction equation

HRID 2394410 reaction equation
[NH:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH:10]=[O:11])[C:4]=2[CH:3]=[CH:2]1.CS(O[CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[O:24][CH3:25])(=O)=O>>[CH3:25][O:24][C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[CH2:17][N:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH:10]=[O:11])[C:4]=2[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 333703Indole-4-carboxaldehydeHCID 18973573HCID 18973573, compound

Product 1

HCID 18973407HCID 18973407, compound

Procedure

The same procedures used in Example 1 were repeated except for using 725 mg of indole-4-carbaldehyde and 2-methoxybenzyl methanesulfonate instead of the benzyl bromide used in Example 1 to give 906 mg of 1-(2-methoxybenzyl)indole-4-carbaldehyde as a yellow oily substance. The yield thereof was found to be 68%.

Sources & evidence

ORD record
ord-f4bf293dbff24662ad02578f5cc3113c
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

Loading…