1-(Bromomethyl)-4-chlorobenzene → HCID 17221114, compound

HRID 2394413Notes

Reaction equation

HRID 2394413 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Br)=[CH:4][CH:3]=1.[NH:10]1[C:18]2[CH:17]=[CH:16][CH:15]=[C:14]([CH:19]=[O:20])[C:13]=2[CH:12]=[CH:11]1>>[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][N:10]2[C:18]3[CH:17]=[CH:16][CH:15]=[C:14]([CH:19]=[O:20])[C:13]=3[CH:12]=[CH:11]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 693291-(Bromomethyl)-4-chlorobenzeneHCID 333703Indole-4-carboxaldehyde

Product 1

HCID 17221114HCID 17221114, compoundYield 99.6%

Procedure

The same procedures used in Example 1 were repeated except for using 2.97 g of 4-chlorobenzyl bromide and 2.00 g of indole-4-carbaldehyde as a starting material to give 3.70 g of 1-(4-chlorobenzyl)indole-4-carbaldehyde as yellow crystals. The yield thereof was found to be 100%.

Sources & evidence

ORD record
ord-5cbbf3bb60e040a486d88a2ec0d9064e
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

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