Pentane, 3-(bromomethyl)- → 1-(2-Ethylbutyl) indole-4-carbaldehyde

HRID 2394417Notes

Reaction equation

HRID 2394417 reaction equation
Br[CH2:2][CH:3]([CH2:6][CH3:7])[CH2:4][CH3:5].[NH:8]1[C:16]2[CH:15]=[CH:14][CH:13]=[C:12]([CH:17]=[O:18])[C:11]=2[CH:10]=[CH:9]1>>[CH2:4]([CH:3]([CH2:6][CH3:7])[CH2:2][N:8]1[C:16]2[CH:15]=[CH:14][CH:13]=[C:12]([CH:17]=[O:18])[C:11]=2[CH:10]=[CH:9]1)[CH3:5]

Participants

3

Reactant 2

HCID 77432Pentane, 3-(bromomethyl)-HCID 333703Indole-4-carboxaldehyde

Product 1

HCID 189733441-(2-Ethylbutyl) indole-4-carbaldehydeYield 60.8%

Procedure

The same procedures used in Example 1 were repeated except for using 4.55 g of 1-bromo-2-ethylbutane and 2.00 g of indole-4-carbaldehyde as a starting material to give 1.92 g of 1-(2-ethylbutyl) indole-4-carbaldehyde as a yellow oily substance. The yield thereof was found to be 61%.

Sources & evidence

ORD record
ord-a471398a0d0842c592e8a5943888ba3c
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

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