Cyclohexane, (bromomethyl)- → HCID 18973350, compound

HRID 2394418Notes

Reaction equation

HRID 2394418 reaction equation
[CH:1]1([CH2:7]Br)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:9]1[C:17]2[CH:16]=[CH:15][CH:14]=[C:13]([CH:18]=[O:19])[C:12]=2[CH:11]=[CH:10]1>>[CH:1]1([CH2:7][N:9]2[C:17]3[CH:16]=[CH:15][CH:14]=[C:13]([CH:18]=[O:19])[C:12]=3[CH:11]=[CH:10]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 137636Cyclohexane, (bromomethyl)-HCID 333703Indole-4-carboxaldehyde

Product 1

HCID 18973350HCID 18973350, compoundYield 84.8%

Procedure

The same procedures used in Example 1 were repeated except for using 4.93 g of cyclohexylmethyl bromide and 2.00 g of indole-4-carbaldehyde as a starting material to give 2.82 g of 1-cyclohexylmethylindole-4-carbaldehyde as a yellow oily substance. The yield thereof was found to be 85%.

Sources & evidence

ORD record
ord-0902207cce8746d59adbf68c3dd206c5
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

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