Indole-3-Carboxaldehyde → HCID 6422043, compound

HRID 2394432Notes

Reaction equation

HRID 2394432 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[O:11])=[CH:2]1.[C:12]1([CH:18](Br)[CH3:19])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH3:19][CH:18]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[O:11])=[CH:2]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 10256Indole-3-CarboxaldehydeHCID 11454(1-Bromoethyl)benzene

Product 1

HCID 6422043HCID 6422043, compound

Procedure

The same procedures used in Example 1 were repeated except for using 870 mg of indole-3-carbaldehyde and α-phenylethyl bromide in place of the benzyl bromide used in Example 1 to give 1.42 g of 1-(α-methylbenzyl)indole-3-carbaldehyde as an orange-colored oily substance. The yield thereof was found to be 95%.

Sources & evidence

ORD record
ord-458b81be13a94f68848d2c2ad1553ad3
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

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