Indole-3-Carboxaldehyde → HCID 18973376, compound

HRID 2394435Notes

Reaction equation

HRID 2394435 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[O:11])=[CH:2]1.CS(O[CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[O:24][CH3:25])(=O)=O>>[CH3:25][O:24][C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[CH2:17][N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[O:11])=[CH:2]1

Participants

3

Reactant 2

HCID 10256Indole-3-CarboxaldehydeHCID 18973573HCID 18973573, compound

Product 1

HCID 18973376HCID 18973376, compound

Procedure

The same procedures used in Example 1 were repeated except for using 870 mg of indole-3-carbaldehyde and 2-methoxybenzyl methanesulfonate in place of the benzyl bromide used in Example 1 to give 926 mg of 1-(2-methoxybenzyl)indole-3-carbaldehyde as pale yellow crystals. The yield thereof was found to be 58%.

Sources & evidence

ORD record
ord-eb76a7e815d94b9ea4136108d6364b51
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

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