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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2394442Generated: October 30, 2026

Phenacyl bromide → 1-(2-Oxo-2-phenylethyl)-1H-indole-3-carboxaldehyde

https://huagongshe.com/reaction/2394442

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenacyl bromideHCID 6259—
ReactantIndole-3-CarboxaldehydeHCID 10256—
Product1-(2-Oxo-2-phenylethyl)-1H-indole-3-carboxaldehydeHCID 96763356.8%

Reaction Steps

The same procedures used in Example 1 were repeated except for using 2.88 g of bromoacetophenone and 2.00 g of indole-3-carbaldehyde as a starting material to give 2.06 g of 1-phenacylindole-3-carbaldehyde as pale yellow crystals. The yield thereof was found to be 57%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05811439
Source datasetuspto-grants-1998_09
ORD IDord-92ae34a0e9744603b5fee13c18377f38
Source noteuspto-grants-1998_09