Phenethyl bromide → HCID 14914492, compound

HRID 2394445Notes

Reaction equation

HRID 2394445 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[O:11])=[CH:2]1.[CH:12]1[CH:17]=[CH:16][C:15]([CH2:18][CH2:19]Br)=[CH:14][CH:13]=1>>[CH2:19]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[O:11])=[CH:2]1)[CH2:18][C:15]1[CH:16]=[CH:17][CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 7666Phenethyl bromideHCID 10256Indole-3-Carboxaldehyde

Product 1

HCID 14914492HCID 14914492, compoundYield 105.5%

Procedure

The same procedures used in Example 7 were repeated except for using 2.00 g of indole-3-carbaldehyde instead of the indole-4-carbaldehyde used in Example 7 and 2.35 g of 2-phenethyl bromide to give 3.34 g of 1-phenethylindole-3-carbaldehyde as a brown oily substance. The yield thereof was found to be 97%.

Sources & evidence

ORD record
ord-5a8fab8a5f4a4915a765bba95404bcad
Source dataset
uspto-grants-1998_09
Patent number
US05811439

Reaction notes

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