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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2394836Generated: October 28, 2026

Diethylamine → N,N-Diethyl-2,5-difluorobenzamide

https://huagongshe.com/reaction/2394836

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylamineHCID 8021—
Reactant2,5-Difluorobenzoyl chlorideHCID 588082—
ProductN,N-Diethyl-2,5-difluorobenzamideHCID 504484894%

Reaction Steps

Diethyl amine (15.4 g, 210 mmol) and 2,5-difluorobenzoyl chloride (17.6 g, 100 mmol) were reacted using General Method E1 to afford 20.0 g of N,N-diethyl-2,5-difluorobenzamide as a clear oil, a 94% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05811411
Source datasetuspto-grants-1998_09
ORD IDord-21b9c4ab4c7a4cd6b21d583204faa99b
Source noteuspto-grants-1998_09