HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Methyl 2-methyl-3-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 2-Methyl-3-nitrobenzoic acid | HCID 16096 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | Methyl 2-methyl-3-nitrobenzoate | HCID 601165 | — |
Reaction Steps
To 2-methyl-3-nitrobenzoic acid (10.0 g) is added methanol (100 ml) and thereto thionyl chloride (8 ml) is added dropwise at room temperature. After reflux for 2 hours, the reaction mixture is poured into ice-water and extracted with dichloromethane. The solvent is concentrated to give methyl 2-methyl-3-nitrobenzoate (10.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05811576 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-0a1ce2c921d84df9b9b7a1effb0ac772 |
| Source note | uspto-grants-1998_09 |