3-Fluoro-p-toluic acid → Methyl 3-fluoro-4-methylbenzoate

HRID 2395011Notes

Reaction equation

HRID 2395011 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5]([OH:7])=[O:6].[CH2:12](OC1C=CC(O)=CC=1CCCC1C=CC(C(OC)=O)=CC=1)C1C=CC=CC=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5]([O:7][CH3:12])=[O:6]

Participants

3

Reactant 2

HCID 676873-Fluoro-p-toluic acidHCID 18973718HCID 18973718, compound

Product 1

HCID 18973767Methyl 3-fluoro-4-methylbenzoate

Procedure

Methyl 3-fluoro-4-methylbenzoate was prepared from 3-fluoro-4-methylbenzoic acid by the process described in Example 6 for the synthesis of methyl 4-(3-(2-benzyloxy-5-hydroxyphenyl)propyl]-benzoate.

Sources & evidence

ORD record
ord-67ef2a72b0d74beab49bb02d26cd2ca6
Source dataset
uspto-grants-1998_09
Patent number
US05811459

Reaction notes

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