methyl 4-[2-(2-benzyloxyphenyl)-(E)-ethenyl]-2-methoxybenzoate → Methyl 4-[3-(2-benzyloxyphenyl)-propyl]-2-methoxybenzoate

HRID 2395022Notes

Reaction equation

HRID 2395022 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH2:16][CH2:17][C:18]1[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[C:20]([OH:28])[CH:19]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:29](OC1C=CC=CC=1/C=C/C1C=CC(C(OC)=O)=C(OC)C=1)C1C=CC=CC=1.C(OC1C=CC=CC=1/C=C/C1C=CC(C(OC)=O)=C(O)C=1)C1C=CC=CC=1>>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH2:16][CH2:17][C:18]1[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[C:20]([O:28][CH3:29])[CH:19]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 18973728methyl 4-[2-(2-benzyloxyphenyl)-(E)-ethenyl]-2-methoxybenzoateHCID 18973756methyl 4-[2-(2-benzyloxyphenyl)-(E)-ethenyl]-2-hydroxybenzoateHCID 18973824Methyl 4-[3-(2-benzyloxyphenyl)propyl]-2-hydroxybenzoate

Product 1

HCID 18973947Methyl 4-[3-(2-benzyloxyphenyl)-propyl]-2-methoxybenzoate

Procedure

Methyl 4-[3-(2-benzyloxyphenyl)-propyl]-2-methoxybenzoate was synthesised from methyl 4-[3-(2-benzyloxyphenyl)-propyl]-2-hydroxybenzoate (prepared as described in Example 15) as described in Example 14 for the synthesis of methyl 4-[2-(2-benzyloxyphenyl)-(E)-ethenyl]-2-methoxybenzoate from methyl 4-[2-(2-benzyloxyphenyl)-(E)-ethenyl]-2-hydroxybenzoate.

Sources & evidence

ORD record
ord-eda9b595784543e1b8004d941b4ee043
Source dataset
uspto-grants-1998_09
Patent number
US05811459

Reaction notes

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