4-[3-(2-Hydroxyphenyl)propyl]benzoate → HCID 178466785, compound

HRID 2395024Notes

Reaction equation

HRID 2395024 reaction equation
C(OC[N:9]1[N:13]=[N:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21]C3C=C(C(=O)C)C=CC=3O)=[CH:16][CH:15]=2)=[N:10]1)(=O)C(C)(C)C.N1C=NN=N1.[OH:37][C:38]1C=CC=C[C:39]=1CCCC1C=CC(C([O-])=O)=CC=1.[CH2:56]([O:63][C:64]1[CH:69]=[CH:68][CH:67]=[CH:66][C:65]=1CCCC1C=CC(C(OC)=O)=CC=1)[C:57]1[CH:62]=[CH:61][CH:60]=[CH:59][CH:58]=1>>[CH2:56]([O:63][C:64]1[CH:65]=[CH:66][C:67]([C:38](=[O:37])[CH3:39])=[CH:68][C:69]=1[CH2:21][CH2:20][C:17]1[CH:16]=[CH:15][C:14]([C:11]2[NH:12][N:13]=[N:9][N:10]=2)=[CH:19][CH:18]=1)[C:57]1[CH:58]=[CH:59][CH:60]=[CH:61][CH:62]=1

Participants

5

Reactant 4

HCID 189738204-[3-(2-Hydroxyphenyl)propyl]benzoateHCID 18973910Methyl 4-[3-(2-benzyloxyphenyl)propyl)benzoateHCID 189739432-(Pivaloyloxymethyl)-5-{-4-[2-(2-hydroxy-5-acetylphenyl)ethyl]phenyl}tetrazoleHCID 178418441HCID 178418441, compound

Product 1

HCID 178466785HCID 178466785, compound

Procedure

2-(Pivaloyloxymethyl)-5-{-4-[2-(2-hydroxy-5-acetylphenyl)ethyl]phenyl}tetrazole was converted to N-2-(pivaloyloxymethyl)-5-{-4--2-(2-benzyloxy-5-acetylphenyl) ethyl]phenyl}tetrazole by the process described in Example 1 for the conversion of 4-[3-(2-hydroxyphenyl)propyl]benzoate to methyl 4-[3-(2-benzyloxyphenyl)propyl]benzoate.

Sources & evidence

ORD record
ord-09d568f37f534045b1fcb5a6edece135
Source dataset
uspto-grants-1998_09
Patent number
US05811459

Reaction notes

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