Hydrochloric Acid → 4-[2-(3-Benzyloxy-2-pyridyl)ethyl]benzoic acid

Participants

Reaction Steps

A solution of methyl 4-[2-(3-benzyloxy-2-pyridyl)ethyl]benzoate (0.1 g, 0.3 mmol) in EtOH (1 ml) was treated with aqueous NaOH solution (0.6 ml 1N). The reaction was stirred at ambient temperature for 18 hours and then treated with HCl soltuion (0.6 ml, 1N). The resulting precipitate was filtered and recrystallised from isopropanol to give the title product.

Provenance & Evidence