Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 7-Methoxyresorufin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Dimethyl Sulfate | HCID 6497 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Resorufin | HCID 69462 | — |
| 촉매 | Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]- | HCID 112414 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 7-Methoxyresorufin | HCID 119220 | 59.5% |
반응 단계
12.1 ml of dimethyl sulphate were added at room temperature while stirring well to a suspension of 20.0 g (85.0 mmol) of resorufin, 17.6 g of freshly powdered potassium carbonate and 10 drops of tris-[2-(2-methoxyethoxy)ethyl]amine in 150 ml of dioxan. The reaction mixture was subsequently stirred at 100° for 2 hours, cooled and then treated with 150 ml of water. The solid was filtered off, washed with water and dried over phosphorus pentoxide. 11.5 g (59.5%) of resorufin methyl ether of m.p. 240°-244° (dec.) were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05811548 |
| 출처 데이터셋 | uspto-grants-1998_09 |
| ORD ID | ord-e2b94f41fb7d44e8a07dc4a93139aed0 |
| 출처 메모 | uspto-grants-1998_09 |