Water → HCID 14457497, compound

Participants

Reaction Steps

To a solution of methyl 4-hydroxybenzoate (7.61 g) in acetone(80 ml) were added geranyl bromide (10.9 g) and potassium carbonate (13.8 g), and then the mixture was refluxed with heating for 6 hours. After the reaction, water (150 ml) was added to the reaction mixture, and the mixture was extracted with chloroform. The organic layer was dried over sodium sulfate anhydride and then concentrated under a vacuum. The residue was purified by silica gel column chromatography (hexane: ethyl acetate=9:1), thereby yielding 13.00 g of methyl 4-geranyloxybenzoate.

Provenance & Evidence