Bromoacetonitrile → HCID 4742453, compound

HRID 2395249Notes

Reaction equation

HRID 2395249 reaction equation
[CH2:1]([N:5]1[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1)[CH:2]([CH3:4])[CH3:3].Br[CH2:12][C:13]#[N:14]>>[NH2:14][CH2:13][CH2:12][N:8]1[CH2:9][CH2:10][N:5]([CH2:1][CH:2]([CH3:4])[CH3:3])[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 11534BromoacetonitrileHCID 20520521-(2-Methylpropyl)piperazine

Product 1

HCID 4742453HCID 4742453, compoundYield 32.2%

Procedure

By using 1-isobutylpiperazine (2.84 g) and bromoacetonitrile(2.40 g), as in the case of Reference Example 28, 1.19 g (15%) of 4-(2-aminoethyl)-1-isobutylpiperazine was obtained.

Sources & evidence

ORD record
ord-7d847c8b6f2047e099b66a8f80315835
Source dataset
uspto-grants-1998_09
Patent number
US05814634

Reaction notes

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