2-Amino-4-chlorobenzoic acid → HCID 22347450, compound

Participants

Reaction Steps

1.10 g (4.15 mmol) of 4-allyloxycarbonylbenzene-sulfonylisocyanate and 712 mg (4.15 mmol) of 2-amino-4-chlorobenzoic acid were treated in the same way as in Example 1 to obtain 657 mg of the above-identified compound (yield 37.6%). Properties: colorless crystal, Melting point: 130°-132° C., PMR (δppm, DMSO-d6): 4.59 (2H,d), 5.18 (1H,d), 5.27 (1H,d), 5.87-5.94 (1H,m), 7.13 (1H,s), 7.22 (1H,d), 7.62-7.70 (2H,m), 7.86 (1H,d), 8.09 (2H,d), 11.63 (1H,br).

Provenance & Evidence