4-Chlorobenzenesulfonyl isocyanate → HCID 18971489, compound

HRID 2395273Notes

Reaction equation

HRID 2395273 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]=[C:12]=[O:13])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH2:14][C:15]1[C:23]([O:24][CH3:25])=[CH:22][CH:21]=[CH:20][C:16]=1[C:17](O)=[O:18]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([N:11]2[C:17](=[O:18])[C:16]3[C:15](=[C:23]([O:24][CH3:25])[CH:22]=[CH:21][CH:20]=3)[NH:14][C:12]2=[O:13])(=[O:9])=[O:10])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 1385874-Chlorobenzenesulfonyl isocyanateHCID 2557202-Amino-3-methoxybenzoic acid

Product 1

HCID 18971489HCID 18971489, compoundYield 84%

Procedure

2.00 g (9.19 mmol) of 4-chlorobenzenesulfonylisocyanate and 1.40 g (8.38 mmol) of 2-amino-3-methoxybenzoic acid were treated in the same way as in Example 1 to obtain 2.58 g of the above-identified compound (yield 84.0%). Properties: colorless crystal, Melting point: 220°-222° C., PMR (δppm, DMSO-d6): 3.88 (3H,s), 7.16 (1H,t), 7.32 (1H,d), 7.43 (1H,d), 7.76 (2H,d), 8.17 (2H,d), 10.95 (1H,br).

Sources & evidence

ORD record
ord-c544c32597154f6cbec44f27af06814a
Source dataset
uspto-grants-1998_09
Patent number
US05814631

Reaction notes

Loading…