Anthranilic Acid → HCID 13950208, compound

HRID 2395286Notes

Reaction equation

HRID 2395286 reaction equation
[C:1]1([S:7]([N:10]=[C:11]=[O:12])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:13][C:14]1[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=1[C:16](O)=[O:17]>>[C:1]1([S:7]([N:10]2[C:16](=[O:17])[C:15]3[C:14](=[CH:22][CH:21]=[CH:20][CH:19]=3)[NH:13][C:11]2=[O:12])(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 227Anthranilic AcidHCID 76096Phenylsulphonyl isocyanate

Product 1

HCID 13950208HCID 13950208, compoundYield 72.4%

Procedure

3.00 g (16.4 mmol) of benzenesulfonylisocyanate and 2.04 g (14.9 mmol) of 2-aminobenzoic acid were treated in the same way as in Example 1 to obtain 3.26 g of the above-identified compound (yield 72.4%). Properties: colorless crystal, Melting point: 211°-213° C., PMR (δppm, DMSO-d6): 7.13 (1H,d), 7.20 (1H,t), 7.61-7.70 (3 H,m), 7.78 (1H,t), 7.87 (1H,d), 8.17 (2H,d), 11.51 (1H,br).

Sources & evidence

ORD record
ord-b9b2085cc51846d490dddad8e8ee0b42
Source dataset
uspto-grants-1998_09
Patent number
US05814631

Reaction notes

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