2-Amino-4-chlorobenzoic acid → HCID 22442380, compound

Participants

Reaction Steps

1.26 g (4.89 mmol) of 1-methyl-4-ethoxycarbonylpyrazol-5-sulfonylisocyanate and 839 mg (4.89 mmol) of 2-amino-4-chlorobenzoic acid were treated in the same way as in Example 1 to obtain 712 mg of the above-identified compound (yield 35.3%). Properties: colorless crystal, Melting point: 222°-224° C., PMR (δppm, DMSO-d6):1.05 (3H,t), 2.09 (3H,s), 4.04 (2H,q), 4.25 (2H,s), 7.15 (1H,s), 7.29 (1H,s), 7.91 (1H,d), 8.02 (1H,s), 11.92 (1H,br).

Provenance & Evidence