2-Amino-4-chlorobenzoic acid → HCID 22347450, compound

Participants

Reaction Steps

1.76 g (6.60 mmol) of 4-allyloxycarbonylbenzenesulfonylisocyanate and 1.13 mg (6.60 mmol) of 2-amino-4-chlorobenzoic acid were treated in the same way as in Example 1 to obtain 965 mg of the above-identified compound (yield 34.8%). Properties: colorless crystal, Melting point: >200° C. (decomposition), PMR (δppm, DMSO-d6):4.87 (2H,d), 5.31 (1H,d), 5.43 (1H,d), 6.00-6.11 (1H,m), 7.12 (1H,s), 7.22 (1H,d), 7.85 (1H,d), 8.23 (2H,d), 8.32 (2H,d), 11.69 (1H,br).

Provenance & Evidence