2-Amino-4-chlorobenzoic acid → HCID 18971419, compound

Participants

Reaction Steps

763 mg (2.44 mmol) of 4-(3-ethyloxycarbonylpropyloxy)benzenesulfonylisocyanate and 418 mg (2.44 mmol) of 2-amino-4-chlorobenzoic acid were treated in the same way as in Example 1 to obtain 306 mg of the above-identified compound (yield 27.0%). Properties: colorless crystal, Melting point: 167°-169° C., PMR (δppm, DMSO-d6):1.18 (3H,s), 1.98-2.03 (1H,m), 2.46 (2H,t), 4.04-4.14 (4H,m), 7.12 (1H,s), 7.16 (2H,d), 7.21 (1H,d), 7.85 (1H,d), 8.09 (2H,d), 11.58 (1H,s).

Provenance & Evidence