189063-46-5 → HCID 18971396, compound

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Reaction Steps

As the starting substances, ethyl 4-chloro-2-phenoxycarbonylaminobenzoate and 4-chloro-2-cyanobenzenesulfonamide were used and the same method was applied as in Example 36 to obtain N-(4-chloro-2-cyanobenzenesulfonyl)-N'-(2-ethyloxycarbonyl-5-chlorophenyl)urea and further to obtain from 1.04 g (2.35 mmol) of N-(4-chloro-2-cyanobenzenesulfonyl)-N'-(2-carboxy-5-chlorophenyl)urea 31 mg of the above-identified compound (yield 3.3%). Properties: colorless crystal, Melting point: >200° C. (decomposition), PMR (δppm, DMSO-d6):7.32-7.36 (2H,m), 7.99 (1H,d), 8.05 (1H,d), 8.38 (1H,d), 8.54 (1H,s), 12.16 (1H,br).

Provenance & Evidence