HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene → 1-[4-(2-Benzoxazolylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene | HCID 520026 | — |
| Reactant | 2-(4-Aminophenylthio)benzoxazole | HCID 13718379 | — |
| Product | 1-[4-(2-Benzoxazolylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)thiourea | HCID 18971648 | 33.3% |
Reaction Steps
2-(4-Aminophenylthio)benzoxazole (10.0 mmoles, 2.6 g) and 4-chloro-3-trifluoromethylphenylisothiocyanate (10.0 mmoles, 2.4 g) were reacted according to procedure A to yield of the title compound 1.6 g, 33%. Mass Spec (FD) 479. Calculated for C21H13ClF3 N3OS2 : C, 52.56; H, 2.73; N, 8.75. Found: C, 52.47; H, 2.70; N, 8.48.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05814646 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-55fb826d6146413b99f115698bf46565 |
| Source note | uspto-grants-1998_09 |