HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene → 1-[4-(2-Quinolylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-isocyanato-2-(trifluoromethyl) benzene | HCID 2733265 | — |
| Reactant | 2-(4-Aminophenylthio)quinoline | HCID 22637130 | — |
| Product | 1-[4-(2-Quinolylthio)phenyl]-3-(4-chloro-3-trifluoromethylphenyl)urea | HCID 18971663 | — |
Reaction Steps
2-(4-Aminophenylthio)quinoline (3.9 mmoles, 1.0 g) and 4-chloro-3-trifluoromethylphenylisocyanate (3.9 mmoles, 0.85 g) were reacted according to procedure A to yield the title compound, 0.8 g, 43%. Mass Spec (FD) 463. Calculated for C23H15ClF3N3OS: C, 58.29; H, 3.19; N, 8.87. Found: C, 58.56; H, 3.43; N. 9.02. M Pt 194°-195° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05814646 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-ba28262cdc5b497d88e56f7fd870ca56 |
| Source note | uspto-grants-1998_09 |