1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene → HCID 56981848, compound

HRID 2395354Notes

Reaction equation

HRID 2395354 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([N:22]=[C:23]=[S:24])=[CH:18][C:17]=1[C:25]([F:28])([F:27])[F:26]>>[N:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[S:8][C:5]1[CH:4]=[CH:3][C:2]([NH:1][C:23]([NH:22][C:19]2[CH:20]=[CH:21][C:16]([Cl:15])=[C:17]([C:25]([F:28])([F:26])[F:27])[CH:18]=2)=[S:24])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 5200261-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzeneHCID 189716604-[(Pyridin-2-yl)sulfanyl]aniline

Product 1

HCID 56981848HCID 56981848, compound

Procedure

2-(4-Aminophenylthio)pyridine (6.0 mmoles, 1.2 g) and 4-chloro-3-trifluoromethylphenylisothiocyanate (6.0 mmoles, 1.4 g) were reacted according to procedure C to yield the title compound, 1.9 g, 72%. Mass spec (FD) 439. Calculated for C19H13ClF3N3 S2 : C, 51.88; H, 2.98, N, 9.55 Found: C, 51.99; H, 3.15; N, 9.63.

Sources & evidence

ORD record
ord-28fa802e5e83429d957b0f07809a1cad
Source dataset
uspto-grants-1998_09
Patent number
US05814646

Reaction notes

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