(4R)-4,5-Dihydro-2-(3-iodophenyl)-4-phenyloxazole → HCID 18665561, compound

HRID 2395369Notes

Reaction equation

HRID 2395369 reaction equation
[F:1][C:2]1[C:10]([I:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].IC1C=C(C2O[CH2:21][C@@H:22]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[N:23]=2)C=CC=1>>[F:1][C:2]1[C:10]([I:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]1[O:5][CH2:21][C@@H:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[N:23]=1

Participants

3

Reactant 2

HCID 18665564(4R)-4,5-Dihydro-2-(3-iodophenyl)-4-phenyloxazoleHCID 18971716HCID 18971716, compound

Product 1

HCID 18665561HCID 18665561, compound

Procedure

4,5-Dihydro-2-(2-fluoro-3-iodophenyl)-4(R)-phenyloxazole was prepared from 2-fluoro-3-iodobenzoyl chloride in a similar manner to that of (+)-4,5-dihydro-2-(3-iodophenyl)-4(R)-phenyloxazole as described in Example 1.

Sources & evidence

ORD record
ord-9398527405484f71a610eaee4d590f9e
Source dataset
uspto-grants-1998_09
Patent number
US05814648

Reaction notes

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