3,4-Diaminobenzoic acid → HCID 178490106, compound

Participants

Reaction Steps

3-(4-(4-Methoxyphenyl)-butoxy)-4-methoxybenzaldehyde (2.8 g) and 3,4-diaminobenzoic acid (1.4 g) were heated to about 120° C. over 1 hour. The resulting residue was chromatographed on a 5×10 cm pad of silica gel eluting with ether to give 1.4 g of a beige solid which was recrystallized from 20 ml of methanol. M.P. 167°-169° C. MS m/e 450 (M+ +1). Elemental analysis calculated for C26H28 O5N2 : C, 69.62; H, 6.29; N, 6.24. Found: C, 69.72; H. 6.70; N, 5.75.

Provenance & Evidence