HCID 10331071, compound → HCID 455374, compound

HRID 2395785Notes

Reaction equation

HRID 2395785 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([CH3:12])[C:9]=1[O:10][CH3:11])[CH2:5]Cl.[CH2:13]([NH:16][C:17]1[C:18]([N:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)=[N:19][CH:20]=[CH:21][CH:22]=1)[CH2:14][CH3:15]>>[CH3:11][O:10][C:9]1[C:2]([CH3:1])=[CH:3][C:4]([CH2:5][N:26]2[CH2:27][CH2:28][N:23]([C:18]3[C:17]([NH:16][CH2:13][CH2:14][CH3:15])=[CH:22][CH:21]=[CH:20][N:19]=3)[CH2:24][CH2:25]2)=[CH:7][C:8]=1[CH3:12]

Participants

3

Reactant 2

HCID 10331071HCID 10331071, compoundHCID 194187982,6-Dimethyl-4-(chloromethyl)anisole

Product 1

HCID 455374HCID 455374, compound

Procedure

Following the general procedure of EXAMPLE 1 and making non-critical variations but starting with 3,5-dimethyl-4-methoxybenzyl chloride (I, PREPARATION 4, 0.41 g) and 1-[3-(propylamino)-2-pyridinyl]piperazine (II, PREPARATION 7, 0.42 g), the title compound is obtained.

Sources & evidence

ORD record
ord-534f1fa3452a4c7c99ec3d5e71bc040f
Source dataset
uspto-grants-1996_02
Patent number
US05489593

Reaction notes

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