5,6-Dimethoyxindole-2-carboxylic acid → HCID 489472, compound

HRID 2395804Notes

Reaction equation

HRID 2395804 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[NH:8][C:7]([C:14]([OH:16])=O)=[CH:6]2.[CH2:17]([NH:19][C:20]1[C:21]([N:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)=[N:22][CH:23]=[CH:24][CH:25]=1)[CH3:18]>>[CH3:18][CH2:17][NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[N:22][C:21]=1[N:26]1[CH2:31][CH2:30][N:29]([C:14]([C:7]2[NH:8][C:9]3[C:5](=[CH:4][C:3]([O:2][CH3:1])=[C:11]([O:12][CH3:13])[CH:10]=3)[CH:6]=2)=[O:16])[CH2:28][CH2:27]1

Participants

3

Reactant 2

HCID 1390355,6-Dimethoyxindole-2-carboxylic acidHCID 10130476N-Ethyl-2-(piperazin-1-yl)pyridin-3-amine

Product 1

HCID 489472HCID 489472, compound

Procedure

Following the general procedure of EXAMPLE 16 and making non-critical variations but using 5,6-dimethoxyindole-2-carboxylic acid (0.50 g) and 1-[3-ethylamino-2-pyridinyl]piperazine (0.51 g), the title compound is obtained,

Sources & evidence

ORD record
ord-35dabcdc7f6747429e4c8b4c12d6606c
Source dataset
uspto-grants-1996_02
Patent number
US05489593

Reaction notes

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