Methyl chloroformate → HCID 141564411, compound

HRID 2395873Notes

Reaction equation

HRID 2395873 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:14][C:13]([O:15][CH3:16])=[C:12]([C:17]3[CH:22]=[CH:21][C:20]([CH2:23][CH2:24][C:25]([O:27][CH3:28])=[O:26])=[CH:19][CH:18]=3)[C:11]2=[O:29])=[CH:6][CH:5]=1)(=[NH:3])[NH2:2].Cl[C:31]([O:33][CH3:34])=[O:32].[OH-].[Na+]>C(Cl)Cl>[CH3:16][O:15][C:13]1[CH2:14][N:10]([C:7]2[CH:8]=[CH:9][C:4]([C:1](=[NH:2])[NH:3][C:31]([O:33][CH3:34])=[O:32])=[CH:5][CH:6]=2)[C:11](=[O:29])[C:12]=1[C:17]1[CH:22]=[CH:21][C:20]([CH2:23][CH2:24][C:25]([O:27][CH3:28])=[O:26])=[CH:19][CH:18]=1

Participants

5

Reactant 3

HCID 6586Methyl chloroformateHCID 14798Sodium HydroxideHCID 18991090HCID 18991090, compound

Product 1

HCID 141564411HCID 141564411, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared from 1-(4-amidinophenyl)-4-methoxy-3-[4-(2-methoxycarbonyl-ethyl)-phenyl]-3-pyrrolin-2-one and methyl chloroformate in methylene chloride with the addition of 0.1N sodium hydroxide solution with vigorous stirring.

Sources & evidence

ORD record
ord-26565a65eb4d4ca4aa34f2abb5044c7c
Source dataset
uspto-grants-1996_02
Patent number
US05489693

Reaction notes

Loading…