Dimethylamine → 3-hydroxy-N,N-dimethylpropane-1-sulfonamide

HRID 2395957Notes

Reaction equation

C([O:4][CH2:5][CH2:6][CH2:7][S:8](Cl)(=[O:10])=[O:9])(=O)C.[CH3:12][NH:13][CH3:14]>>[OH:4][CH2:5][CH2:6][CH2:7][S:8]([N:13]([CH3:14])[CH3:12])(=[O:10])=[O:9]

Participants

Reactant 2

HCID 674Dimethylamine

HCID 105842113-(Chlorosulfonyl)propyl acetate

Product 1

HCID 152348883-hydroxy-N,N-dimethylpropane-1-sulfonamide

Procedure

Using 3-acetoxy-1-propanesulfonylchloride and dimethylamine, substantially the same reaction was conducted as in reference example 47 and 48 to produce the title compound.

Workup

customsubstantially the same reaction

Sources & evidence

ORD record: ord-04777152818545948ab9960f66f2ad29
Source dataset: uspto-grants-1996_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05491145

Reaction notes

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