6-Chloro-7-methylimidazo[1,2-b]pyridazine → HCID 18988140, compound

HRID 2395966Notes

Reaction equation

HRID 2395966 reaction equation
Cl[C:2]1[C:3]([CH3:11])=[CH:4][C:5]2[N:6]([CH:8]=[CH:9][N:10]=2)[N:7]=1.CN(C=[N:16][S:17]([CH2:20][CH2:21][CH2:22][C:23]([CH2:28][CH3:29])([CH2:26][CH3:27])[CH2:24][OH:25])(=[O:19])=[O:18])C>>[CH2:28]([C:23]([CH2:26][CH3:27])([CH2:22][CH2:21][CH2:20][S:17](=[O:19])(=[O:18])[NH2:16])[CH2:24][O:25][C:2]1[C:3]([CH3:11])=[CH:4][C:5]2[N:6]([CH:8]=[CH:9][N:10]=2)[N:7]=1)[CH3:29]

Participants

3

Reactant 2

HCID 122483366-Chloro-7-methylimidazo[1,2-b]pyridazineHCID 54474572HCID 54474572, compound

Product 1

HCID 18988140HCID 18988140, compound

Procedure

Using 0.8 g of 6-chloro-7-methylimidazo[1,2-b]pyridazine and 1.52 g of 5-(N,N-dimethylaminomethylene)aminosulfonyl-2,2-diethyl-1-pentanol, 0.84 gof the title compound was obtained in the same manner as in Example 14.

Sources & evidence

ORD record
ord-5487c52ad15d467c908fdeb08c63af9e
Source dataset
uspto-grants-1996_02
Patent number
US05491145

Reaction notes

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