6-Chloro-7-methylimidazo[1,2-b]pyridazine → HCID 21800330, compound
Reaction equation
[Cl:1][C:2]1[C:3]([CH3:11])=[CH:4][C:5]2[N:6]([CH:8]=[CH:9][N:10]=2)[N:7]=1.CN(C=[N:16][S:17]([CH2:20][CH:21]([CH:24]([CH3:26])[CH3:25])[CH2:22][OH:23])(=[O:19])=[O:18])C>>[ClH:1].[CH:24]([CH:21]([CH2:20][S:17](=[O:19])(=[O:18])[NH2:16])[CH2:22][O:23][C:2]1[C:3]([CH3:11])=[CH:4][C:5]2[N:6]([CH:8]=[CH:9][N:10]=2)[N:7]=1)([CH3:26])[CH3:25]Participants
3
Procedure
Using 0.8 g of 6-chloro-7-methylimidazo[1,2-b]pyridazine and 1.29 g of 3-(N,N-dimethylaminomethylene)aminosulfonyl-2-isopropyl-1-propanol, 1.37 gof the title compound was obtained in the same manner as in Examples 14 and
Sources & evidence
- ORD record
- ord-736f8dd41b2f43819df0cab870809374
- Source dataset
- uspto-grants-1996_02
- Patent number
- US05491145
Reaction notes
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