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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396005Generated: October 30, 2026

3-Chloro-2-methylbenzoic acid → HCID 53732632, compound

https://huagongshe.com/reaction/2396005

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-2-methylbenzoic acidHCID 82010—
Reactant3-AminoquinuclidineHCID 123238—
Reactant(S)-quinuclidin-3-amineHCID 719216—
ProductHCID 53732632HCID 53732632—

Reaction Steps

Proceeding as in Example 1, Method A, but replacing 2,3-dimethylbenzoic acid with 3-chloro-2-methylbenzoic acid and (RS)-3-amino-1-azabicyclo[2.2.2]octane with (S)-3-amino-1-azabicyclo[2.2.2]octane gave (S)-N-(1-azabicyclo[2.2.2]oct-3-yl)-3-chloro-2-methylbenzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05491148
Source datasetuspto-grants-1996_02
ORD IDord-38e982e88c8a4056ba8ab3eedcff749c
Source noteuspto-grants-1996_02