Sulfuryl chloride → HCID 18988317, compound

HRID 2396034Notes

Reaction equation

HRID 2396034 reaction equation
[Cl:1][C:2]1[C:3]([O:7][CH3:8])=[N:4][S:5][N:6]=1.S(Cl)([Cl:12])(=O)=O>C(Cl)(Cl)(Cl)Cl>[Cl:1][C:2]1[C:3]([O:7][CH2:8][Cl:12])=[N:4][S:5][N:6]=1

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 181772483-Chloro-4-methoxy-1,2,5-thiadiazole

Product 1

HCID 18988317HCID 18988317, compoundYield 79.3%

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent2×

Procedure

A solution comprised of 5 g of 60 percent pure 4-chloro-3-methoxy-1,2,5-thiadiazole in 30 mL of carbon tetrachloride was irradiated over a period of 45 minutes at 80° C. with a sunlamp while adding a solution comprised of 5 g of sulfuryl chloride in 20 mL of carbon tetrachloride. The reaction mixture was then washed with 30 mL of asaturated aqueous sodium bicarbonate solution and concentrated under reduced pressure to yield 4.87 grams of 4-chloro-3-chloromethoxy-1,2,5-thiadiazole.

Workup

  1. customwas irradiated over a period of 45 minutes at 80° C. with a sunlamp
  2. additionwhile adding a solution
  3. washThe reaction mixture was then washed with 30 mL of asaturated aqueous sodium bicarbonate solution
  4. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-de5b792ee78647d1a951cedeb685ff17
Source dataset
uspto-grants-1996_02
Patent number
US05491155

Reaction notes

Loading…