Dichloromethane → HCID 57097879, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of the title compound of Step E above (2.2 g, 0.005 mol) in25 ml methylene chloride cooled to 0° C. was added triethylamine (1.0 g) and hexyl (chlorosulfenyl)(methyl)carbamate, (prepared in a mannersimilar to Example 1, Step D), (2.5 g 75% pure) dropwise at 0° C. The mixture was stirred at room temperature for additional one hour. The reaction mixture was concentrated under high vacuum and subjected to silica gel column chromatography using hexane-ether (1:1) as an eluent. The title compound (2.5 g) was obtained, melting point 128°-129° C. in high purity.

Provenance & Evidence