HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 54260772, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Acetic acid, chloro(phenylthio)-, ethyl ester | HCID 11117878 | — |
| Reactant | HCID 53868356 | HCID 53868356 | — |
| Catalyst | Zinc acetate (USP) | HCID 2724192 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 54260772 | HCID 54260772 | — |
Reaction Steps
Part B. The method of Speckamp et al., Tetrahedron Letters, v. 32, p. 1491 (1991), is employed here. Thus, a solution of ethyl 2-chloro-2-(phenylthio)acetate [prepared according to the method of Bohme et al., Liebigs Annalen der Chemie, p. 51 (1977)], 7-heptadecen-10-ol, andcatalytic zinc acetate dihydrate in benzene is heated to reflux under a Dean-Stark trap until the formation of hydrogen chloride is complete. Workup according to the listed reference affords ethyl 2-(1-heptyl-3-decen-1-oxy)-2-(phenylthio)acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05491152 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-78ae3be7a50b40869bcd31437823f248 |
| Source note | uspto-grants-1996_02 |