反应详情

温度

90 °C

10.0 g of Z-1,2-diphenyl-1-[4-(bromoethoxy)phenyl]-1-buten-4-ol is added to200 ml of ethanol saturated with ammonia gas. The solution is stirred for 3hours at 90° C. in an autoclave. The solvent is evaporated and the residue is dissolved in ethyl acetate in the presence of 2M sodium hydroxide solution by warming the solution on a water bath. The organic layer is washed with water. The precipitated product is filtered off. The yield is 5.1 g (60%).

1. customThe solvent is evaporated
2. dissolutionthe residue is dissolved in ethyl acetate in the presence of 2M sodium hydroxide solution
3. temperatureby warming the solution on a water bath
4. washThe organic layer is washed with water
5. filtrationThe precipitated product is filtered off