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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396170Generated: November 1, 2026

AKOS B013900 → HCID 15341212, compound

https://huagongshe.com/reaction/2396170

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAKOS B013900HCID 6485564—
ReactantPravastatin Diol Lactone Di-(tert-butyldimethylsilyl) EtherHCID 14600906—
ProductHCID 15341212HCID 1534121298%

Reaction Steps

A procedure similar to that described in Example 1, above, was followed, but using 0.72 g of (2RS)-2-(4-fluorophenoxy)butyric acid and 1.0 g of (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above], to give 1.30 g of the title compound as a colorless foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05491167
Source datasetuspto-grants-1996_02
ORD IDord-1104a796f98a4532bc9708c5b3159163
Source noteuspto-grants-1996_02