Tetrabutylammonium Fluoride → HCID 54086466, compound

Participants

Reaction Steps

A procedure similar to that described in Example 2, above, was followed, but using 719 mg of (4R,6R)-6-([1S,2S,6S,8S,8aR]-2-{1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-[(2RS)-2-(1-naphthyloxy)butyryloxy]-2-methyl-1-naphthyl}ethyl)tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example 46, above] and 18.8 ml of a 1.0 molar solution of tetrabutylammonium fluoride in tetrahydrofuran, to give 272 mg of the title compound as white crystals, melting at between 138° and 140° C.

Provenance & Evidence