Tetrabutylammonium Fluoride → HCID 53660498, compound

Participants

Reaction Steps

A procedure similar to that described in Example 2, above, was followed, but using 1.44 g of ([1S,2S,6S,8S,8aR]-2-{1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-[(2RS)-2-(2,4,6-trimethylphenoxy)butyryloxy]-2-methyl-1-naphthyl}ethyl)tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example 58, above] and 38.0 ml of a 1.0 molar solution of tetrabutylammonium fluoride in tetrahydrofuran, to give 694 mg of the desired compound as white crystals, melting at between 134° and 136° C.

Provenance & Evidence