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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2396198Generated: November 3, 2026

Clofibric Acid → HCID 54450117, compound

https://huagongshe.com/reaction/2396198

Reaction equation

Participants

RoleNameHCIDCharge
ReactantClofibric AcidHCID 2797—
ReactantPravastatin Diol Lactone Di-(tert-butyldimethylsilyl) EtherHCID 14600906—
ProductHCID 54450117HCID 54450117—

Reaction Steps

A procedure similar to that described in Example 10, above, was followed, but using 0.78 g of 2-(4-chlorophenoxy)-2-methylpropionic acid and 1.0 g of (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl}ethyl)tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above], to give1.08 g of the title compound as a colorless foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05491167
Source datasetuspto-grants-1996_02
ORD IDord-6f2c4b324b604074922736a7d84372da
Source noteuspto-grants-1996_02