Tetrabutylammonium Fluoride → HCID 131719258, compound

Participants

Reaction Steps

A procedure similar to that described in Example 2, above, was followed, but using 1.42 g of (4R,6R)-6-([1S,2S,6S,8S,8aR]-2-{1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-[(2RS)-2-(4-isopropylphenoxy)butyryloxy]-2-methyl-1-naphthyl}ethyl)tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as describedin Example 115, above] and 38.0 ml of a 1.0 molar solution of tetrabutylammonium fluoride in tetrahydrofuran, to give 80 mg of the titlecompound as a pale yellow powder.

Provenance & Evidence