HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-METHYLPHENOXY)PROPANOIC ACID → HCID 57043904, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-METHYLPHENOXY)PROPANOIC ACID | HCID 165592 | — |
| Reactant | Pravastatin Diol Lactone Di-(tert-butyldimethylsilyl) Ether | HCID 14600906 | — |
| Product | HCID 57043904 | HCID 57043904 | 80.3% |
Reaction Steps
A procedure similar to that described in Example 1, above, was followed, but using 0.65 g of (2RS)-2-(2-methylphenoxy)propionic acid and 1.0 g of (4R,6R)-6-{(1S,2S,6S,8S,8aR)-2-[1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above], to give 1.04 g of the title compound as a colorless foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05491167 |
| Source dataset | uspto-grants-1996_02 |
| ORD ID | ord-74ed8d23bbf24ef5af6e0d22f11f103b |
| Source note | uspto-grants-1996_02 |